Strengthening Apollo's global patent position - Transdermal delivery
Apollo has strengthened the positioning of its transdermal delivery platform with a suite of new patent applications, based on recently completed developments.

The additional patent applications build on the delivery platform’s “foundation” international (PCT) patent application and cover novel formulations that can deliver more concentrated amounts of active cosmetic or therapeutic agents into the skin.

Additionally, a significant body of data collected in the first six months of 2007 has provided valuable supporting evidence for particular therapeutic and R&D applications covered by the PCT application, which claims 22nd December 2005 as its earliest priority date.

Apollo has also rebranded its transdermal delivery technology as Intradel™, to be used globally, replacing the TransD™ mark. Apollo owns the registered TransD® trade mark in Australia in relation to various medicated preparations, but did not pursue registration in the US following correspondence from a major pharmaceutical company. A subsidiary of Johnson & Johnson, Alza Corporation, indicated that it would block the registration because it owns an existing D-Trans® mark, registered in the US in relation to drug development services on the basis of “likelihood of confusion”.

According to Apollo’s Head of Intellectual Property, Dr Gavin Dixon, “The new name sends the message that we have a “single mark” trade registration across all major jurisdictions including the US and EU and it brings the new name into line with our Oradel™ oral delivery system ” he said.

“The name change makes commercial sense, and indicates to the market that the technology is even more wide ranging than originally thought” he added.

Intradel™ formulations consist of nano (or micro)-sized water droplets surrounded by specialized oil and surfactant blends, and which carry therapeutic or cosmetic agents through the skin.

     
INTRADEL™ particles are up to ten times smaller than regular skin creams  Oil/surfactant allows partitioning of lipid matrix
(part of outer skin layer)
for particle entry 
Particles are highly deformable to squeeze through micro pores in the skin 
  
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